Employment data are from the U.S. Department of Labor's Bureau of Labor Statistics, Occupational Employment and Wage Statistics and Employment Projections programs. State-level projections data are from Projections Central and State Labor Market Information offices.

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          Current Employment for Registered Nurses in MISSOURI

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          Rank Region 2025 Employment
          1 St. Louis, MO-IL Metro Area 35,200
          2 Kansas City, MO-KS Metro Area 29,650
          3 Springfield, MO Metro Area 6,820
          4 Columbia, MO Metro Area 3,680
          5 Southeast Missouri Balance of State 3,650
          6 Central Missouri Balance of State 2,800
          7 Joplin, MO-KS Metro Area 2,670
          8 North Missouri Balance of State 2,020
          9 Jefferson City, MO Metro Area 1,910
          10 St. Joseph, MO-KS Metro Area 1,490
          11 Cape Girardeau, MO-IL Metro Area 1,470
          12 Southwest Missouri Balance of State 1,270